In 1830s Mexico, Carolina Fuentes wants to prove she's a better slayer than wife, defying her father who wants her married off safely. Lalo Villalobos had a perfectly dull life until a vampiro turned him while he was trying to avenge his parents' murder. He heads to the pueblo where the first vampiro was made, seeking a cure. Instead he collides with Carolina, who'd gladly put a dagger through his heart. They discover a common enemy and must work together.